Tuo Nanou Tiéba

Quantative STRUCTURE Activity Relationship (QSAR) Study of a Series of Molecules Derived from 2,3-dihydro-1H- perimidine having Activity against Protein Tyrosine Phosphatase 1B

Tuo Nanou Tiéba, Dembélé Georges Stéphane, Soro Doh, Konate Bibata, Kodjo Charles Guillaume & ZIAO Nahossé · International Research Journal of Pure and Applied Chemistry · 2021

In order to study the Quantitative Structure Activity Relationship (QSAR) against protein tyrosine phosphatase 1B and descriptors, we used a series of fourteen (14) molecules derived from perimidine. The compounds were optimized at the computational level B3LYP / 6-31 G (d, p), t...

Open access Research Article 10.9734/irjpac/2021/v22i830426

Study of Reactivity and Molecular Stability by the Density Functional Theory Method on 2,3-Dihydro -1H-Perimidine: Comparative Analysis

Tuo Nanou Tiéba, Soro Doh, Konate Bibata, Kodjo Charles Guillaume, Yapo Ossey Bernard & ZIAO Nahossé · Chemical Science International Journal · 2021

Numerous studies have been carried out on the structure of 2,3-dihydro-1H-perimidine substituted as compounds with various biological activities. Researchers have found that these compounds exhibit characteristics potentially useful in medicinal chemistry research and have many t...

Open access Research Article 10.9734/CSJI/2021/v30i430227

A New Heterocyclic 1H-perimidine synthesized 2-(2,3-dihydro-1H-périmidin-2yl-)-6-methoxyphenol: Evaluation of Acute Toxicity in Wistar Rat

Tuo Nanou Tiéba, Pacôme Kouadio N’Go, BALLO Daouda, Kangah Niameke Jean Baptiste, Kodjo Charles Guillaume, Yapo Ossey Bernard & ZIAO Nahossé · Journal of Pharmaceutical Research International · 2021

Background and Aim: The 1H-perimidne, as novel source carbene ligand, is well known for its anti-fungal, anti-microbial or anti-tumor activities. Here, we aimed to study the acute toxicity in Wistar rat of 2-(2,3-dihydro-1H-perimidin-2-yl)-6-methoxyphenol, a new heterocyclic 1H-...

Open access Research Article 10.9734/jpri/2021/v33i24B31441