Tomoyoshi Nozaki

Metronidazole Induces the Metazoan Death of Giardia Trophozoites with the Aid of Pyruvate

Dibyendu Raj, Tomoyoshi Nozaki, Shanta Dutta & Sandipan Ganguly · International Journal of TROPICAL DISEASE & Health · 2024

Background: Metronidazole is the most common drug for the treatment of infectious agent Giardia. The trophozoites need to fight against the oxidative stress generated by metronidazole for their survival. It has been reported that trophozoites possesses several enzymes involved in...

Open access Research Article 10.9734/ijtdh/2024/v45i11510

Transcriptome Analysis of Entamoeba histolytica Trophozoites during in vivo Contact-independent Mediated Host-parasite Interaction: Putative Pathways Related to PCD

David Guillermo Pérez Ishiwara, Mineko Shibayama, Kumiko Nakada-Tsukui, Ghulam Jeelani, María del Consuelo Gómez-García, Olivia Medel Flores & Tomoyoshi Nozaki · Microbiology Research Journal International · 2022

Aim: In the present study, we exploited DNA microarray-based transcriptome analysis and showed overall changes in gene expression in vivo of amoebic trophozoites that interact with animal soluble factors using an intraperitoneal dialysis bag model to elucidate putative molecular...

Open access Research Article 10.9734/mrji/2022/v32i530390