Tapas Panda

Novel Salts of Sunitinib an Anticancer Drug with Improved Solubility

Sangeeta Sangwan, Tapas Panda, Ram Thiamattam, Sharwan K. Dewan & Rajesh K. Thaper · International Research Journal of Pure and Applied Chemistry · 2014

Polymorph, co-crystal and salt screening experiments were carried out to identify novel solid forms with the improved physicochemical properties, particularly water solubility in the present case. Co-crystal formation was evaluated with urea and nicotinamide. These coformers do n...

Open access Research Article 10.9734/IRJPAC/2015/13578

Synthesis and Characterization of Impurities of a Common and Advanced Intermediate of Candesartan and Azilsartan Antihypertensive Drugs

Sangeeta Sangwan, Tapas Panda, Kaushal Nayyar, Sharwan K. Dewan & Rajesh K. Thaper · International Research Journal of Pure and Applied Chemistry · 2014

Six impurities were identified in the lab development batches during the course of benzimidazole intermediate (1) synthesis by reverse phase HPLC method. Intermediate 1 is used as a common and advanced intermediate in the synthesis of candesartan and azilsartan. All the impuritie...

Open access Research Article 10.9734/IRJPAC/2015/13162