Taiwo, F. O

Synthesis of (Z)-2-((2-(Benzylideneamino)ethyl)Amino)-3-Methylquinoxaline-6-Sulfonyl Azide Derivatives and Their Acetylcholinesterase and Butyryl Cholinesterase Inhibitory Activities

Taiwo, F. O, O. B. Omoyeni, I. J. Olawuni, E. G. Fakola & C. A. Obafemi · Journal of Applied Life Sciences International · 2026

Aims: This study synthesized  a series of (Z)-2-((2-(benzylideneamino)ethyl)amino)-3-methylquinoxaline-6-sulfonyl azide derivatives and evaluated their inhibitory activities against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Methods: The derivatives were prepar...

Open access Research Article 10.9734/jalsi/2026/v29i5800

Design and Synthesis of 1-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one Derivatives as a Selective Inhibitor for Acetylcholinesterase and Butyryl Cholinesterase

Taiwo, F. O, Omoyeni, O. B, Olawuni, I. J, Fakola, E. G & Obafemi, C. A. · Journal of Applied Life Sciences International · 2026

Quinoxaline-based heterocycles are of interest as potential cholinesterase inhibitors, and this study evaluated a substituted 1-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one series against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). The objective was to synt...

Open access Research Article 10.9734/jalsi/2026/v29i5798