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Tadashi Fujii

Publications (6)

Minimally Age-Dependent Gut Microbial Signatures in Pancreatic Neoplasia Identified by qPCR Targeting the but Gene

Tadashi Fujii, Eizaburo Ohno, Yoshiki Hirooka & Takumi Tochio · Microbiology Research Journal International · 2026

Background & Aims: Age-related variation in the gut microbiota complicates biomarker discovery for pancreatic cancer. This study aimed to identify microbial taxa with minimal age dependence that are associated with pancreatic neoplasia and to develop a practical quantitative...

Open access Research Article 10.9734/mrji/2026/v36i41737

Clinical and Microbial Insights into the Therapeutic Potential of 1-Kestose in Managing Crohn’s Disease

Tadashi Fujii, Takumi Tochio, Erika Teramura, Masaya Sano, Mia Fujisawa, Takayoshi Suzuki, Kohei Funasaka, Eizaburo Ohno, Yoshiki Hirooka & Masashi Matsushima · Microbiology Research Journal International · 2026

Background and Aims: Crohn’s disease (CD) is a chronic inflammatory bowel disease characterized by gastrointestinal inflammation, with gut microbiota dysbiosis playing a key role in its onset and progression. This study aimed to evaluate whether 1-kestose supplementation modulate...

Open access Research Article 10.9734/mrji/2026/v36i31718

Gut microbiota Alterations Associated with 1-kestose Supplementation and Owner-reported Aggression-related Behaviors in Dogs

Tadashi Fujii, Saki Yamakawa, Nobuhiro Kondo, Takayuki Asahina, Kohei Funasaka, Eizaburo Ohno, Yoshiki Hirooka, Takumi Tochio & Chie Mogi · Microbiology Research Journal International · 2026

Aims: To characterize fecal gut microbiota features associated with a history of aggression in dogs and to explore whether supplementation with the prebiotic fructooligosaccharide 1-kestose is associated with alterations in gut microbiota composition and owner-reported aggression...

Open access Research Article 10.9734/mrji/2026/v36i21705

Fecal and Salivary Microbial Gene Markers for the Non-invasive Detection of Colorectal Cancer Progression

Naoko Nakano, Tadashi Fujii, Hideaki Takahashi, Kotoyo Fujiki, Kohei Funasaka, Eizaburo Ohno, Yoshiki Hirooka & Takumi Tochio · Microbiology Research Journal International · 2026

Aims: To evaluate the diagnostic potential of previously reported (5ar, nan) and novel microbial gene markers in fecal and salivary microbiomes for the non-invasive detection of colorectal cancer (CRC) progression. Study Design: Cross-sectional study. Place and Duration of Study:...

Open access Research Article 10.9734/mrji/2026/v36i41730

Assessment of Risk for Immune and Psychiatric Disorders Using qPCR-Based Monitoring of the nan Gene in Gut Microbiota: A Non-invasive Approach

Mitsuo Nagasaka, Tadashi Fujii, Toshiaki Kamano, Seiya Mihara, Kohei Funasaka, Eizaburo Ohno, Chie Mogi, Yoshiki Hirooka & Takumi Tochio · Microbiology Research Journal International · 2024

Aim: This study aimed to establish a non-invasive, rapid, and cost-effective method to assess the potential risk of immune and psychiatric disorders by quantifying nan gene levels in gut microbiota, specifically focusing on Ruminococcus gnavus and other Lachnospiraceae species as...

Open access Research Article 10.9734/mrji/2024/v34i111503

Clinical Effects of a Parasynbiotic Combining 1-Kestose and Lactiplantibacillus plantarum FM8 on Feline Atopic Skin Syndrome: A Pilot Study

Hideaki Takahashi, Koji Kawano, Keita Iyori, Tadashi Fujii, Kento Kuramitsu, Akira Ueyama, Hazumu Amatsuji, Yun-Hsia Hsiao, Takayuki Asahina, Nobuhiro Kondo, Eizaburo Ohno, Kohei Funasaka, Yoshiki Hirooka & Takumi Tochio · Microbiology Research Journal International · 2025

Aims: Feline atopic skin syndrome (FASS) is a chronic inflammatory skin disease characterized by pruritus and typical lesions such as erythema, papules, excoriations, and lichenification. Although the relationship between gut microbiota and atopic dermatitis is well-documented in...

Open access Research Article 10.9734/mrji/2025/v35i101643