Sunday J. Ameh, Nneka N. Ibekwe, Aminu A. Ambi, Taoheed Abdulkareem, Barnabas K. Toge, Benjamin U. Ebeshi, John Alfa & Magaji Garba·European Journal of Medicinal Plants·2014
Introduction: An “aroma-active compound” (AAC) has a “flavor”- ie: a “distinct taste and odor”. An example is menthol. All aromatic plants (APs), including some medicinal plants, such as Mentha×piperita (Family Lamiaceae), produce a group of fat-soluble secondary metabolites call...
Open access
Research Article10.9734/EJMP/2014/10779
Background: The World Health Organization (WHO) recommended that the toxicity data of a traditional medicine (TM) product that has been in use for 20 years or more without untoward effects should be determined, as the first step in its research and development (R&D). Such dat...
Open access
Research Article10.9734/BJPR/2014/10617
Sunday J. Ameh, Nneka Ibekwe, Aminu Ambi, Obiageri Obodozie, Mujtaba Abubakar, Magaji Garba, Herbert Cocker & Karniyus S. Gamaniel·European Journal of Medicinal Plants·2014
Background: Herbal drug standardization (HDS) is multidisciplinary with botany and chemistry working together to facilitate decisions on production of herbal medicines. The common reasons for HDS are: i) it creates the need for establishing botanical identity; ii) it is necessary...
Open access
Research Article10.9734/EJMP/2014/5457
This review aims to sensitize researchers, regulators and other stakeholders to the centrality of clinical research to drug development from herbs used in Traditional Medicine (TM). The review uncovered and dwelt on the fact that: while clinical trials of chemical medicines (phar...
Historically, drug discovery from natural products has been a time and resource-intensive process. Bioassay-guided isolation of natural products often leads to already known compounds of limited, or no chemical or pharmacological interest. Some bioactive compounds are unstable an...
Open access
Research Article10.9734/IRJPAC/2015/14458