Suganthini Krishnan Natesan

In vivo Efficacy of Posaconazole (POS) against Voriconazole Resistant (VCZ-R) Aspergillus flavus in an Inhalational Neutropenic Murine Model of Invasive Pulmonary Aspergillosis

Suganthini Krishnan Natesan & Jessica L. Cutright · Microbiology Research Journal International · 2019

Invasive aspergillosis (IA) is a life-threatening infection in patients with cancer. Recent studies have reported that non-fumigatus Aspergillus spp., including Aspergillus flavus, are emerging as predominant pathogens in various transplant and cancer centers in the USA and aroun...

Open access Research Article 10.9734/mrji/2019/v29i330163

Change in Expression of Genes Involved in the G-Protein Signaling Pathway (GP-SP) is Associated with Voriconazole-Resistance (VCZ-R) in Aspergillus Species

Suganthini Krishnan Natesan, Lulu Farhana & Wenjuan Wu · Microbiology Research Journal International · 2018

Background: Invasive infections due to Aspergillus species continue to be associated with a significant morbidity in immuno-compromised patients. Despite the availability of several azoles [isavuconazole (ISZ), posaconazole (POS), voriconazole (VCZ) and itraconazole (ITZ)], morta...

Open access Research Article 10.9734/MRJI/2018/44716