Stephen Eyije Abechi

Assessment of Heavy Metals Level of Soil in Kakuri Industrial Area of Kaduna, Nigeria

Edith Bolanle Agbaji, Stephen Eyije Abechi & Solomon Arome Emmanuel · Journal of Scientific Research and Reports · 2014

Aim: To determine the level and distribution of Zn, Cu, Ni, Cr, Pb, Hg and V from soils in the vicinities of Kakuri industrial area of Kaduna state, Nigeria. Study Design: To compare the soil heavy metal concentrations with regulatory standard values permitted by the Nigerian env...

Open access Research Article 10.9734/JSRR/2015/13212

QSAR Study of Series of HEPT (1-[(2-hydroxyethoxy) methyl]-6-(phenylthio)thyio)thymine) Derivatives Using Genetic Function Approximation as Anti-HIV-1 Agents

Emmanuel Israel Edache, Adamu Uzairu & Stephen Eyije Abechi · Current Journal of Applied Science and Technology · 2015

Aims/Objectives: Studies were performed to correlate the biological activity of the HEPT (1-[(2-hydroxyethoxy) methyl]-6-(phenylthio)thyio)thymine) 107 sets of compound with the independent descriptor to know the structural requirement of the drug receptor binding interaction. Me...

Open access Research Article 10.9734/BJAST/2016/21791

Development and Estimation of an in Silico Model for Anti-HIV-1 Integrase Inhibitor Using Genetic Function Approximation

Emmanuel Israel Edache, Adamu Uzairu & Stephen Eyije Abechi · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Aim: Integrase inhibitors are an essential enzyme required for replication of the acquired immunodeficiency syndrome virus. It is a potent target for anti- HIV therapy. A QSAR study is performed on the series indole -diketo, diketo acid and carboxamide derivatives in order to ana...

Open access Research Article 10.9734/JAMPS/2016/22227