Soro Doh

Study of Reactivity and Molecular Stability by the Density Functional Theory Method on 2,3-Dihydro -1H-Perimidine: Comparative Analysis

Tuo Nanou Tiéba, Soro Doh, Konate Bibata, Kodjo Charles Guillaume, Yapo Ossey Bernard & ZIAO Nahossé · Chemical Science International Journal · 2021

Numerous studies have been carried out on the structure of 2,3-dihydro-1H-perimidine substituted as compounds with various biological activities. Researchers have found that these compounds exhibit characteristics potentially useful in medicinal chemistry research and have many t...

Open access Research Article 10.9734/CSJI/2021/v30i430227

Theoretical Study of the Chemical Reactivity of a Series of 2, 3-Dihydro-1H-Perimidine

Nanou Tieba Tuo, Georges Stephane Dembele, Soro Doh, Fandia Konate, Bibata Konate, Charles Guillaume Kodjo & Nahossé Ziao · International Research Journal of Pure and Applied Chemistry · 2022

This reactivity study was performed on seven molecules of a 2,3-dihydro-1H-perimidine series using density functional theory at the B3LYP / 6-311 G (d, p) level. Calculation of the dipole moment showed that compound 4 is more soluble in aqueous medium. The study of frontier molec...

Open access Research Article 10.9734/irjpac/2022/v23i130451

Quantative STRUCTURE Activity Relationship (QSAR) Study of a Series of Molecules Derived from 2,3-dihydro-1H- perimidine having Activity against Protein Tyrosine Phosphatase 1B

Tuo Nanou Tiéba, Dembélé Georges Stéphane, Soro Doh, Konate Bibata, Kodjo Charles Guillaume & ZIAO Nahossé · International Research Journal of Pure and Applied Chemistry · 2021

In order to study the Quantitative Structure Activity Relationship (QSAR) against protein tyrosine phosphatase 1B and descriptors, we used a series of fourteen (14) molecules derived from perimidine. The compounds were optimized at the computational level B3LYP / 6-31 G (d, p), t...

Open access Research Article 10.9734/irjpac/2021/v22i830426

DFT and TD-DFT Study of the Structure-Cytotoxic Activity Relationship of Ruthenium Polypyridine Complexes Derived from RuCl2(azpy)2

N’guessan Kouakou Nobel, Niameke Kangah Jean Baptiste, Ehouman Jean Missa, Dembélé Georges Stéphane, Soro Doh, Ouattara Patrice, Bamba Kafoumba & ZIAO Nahossé · Asian Journal of Physical and Chemical Sciences · 2026

Ruthenium polypyridine complexes are of interest because of their cytotoxic activity and their lower toxicity relative to cisplatin. This study applies density functional theory and time-dependent density functional theory to examine structure–cytotoxic activity relationships in...

Open access Research Article 10.9734/ajopacs/2026/v14i3345

Study by Molecular Docking of the Interactions between Dihydroorotate Dehydrogenase and a Series of Inhibitors of Pyrrole Derivatives for the treatment of Malaria

Niaré Adama, Attia Yapo John Alex, Djako Akassa Marius Bernard, Kambiré Sobamfou Marius, Dembélé Georges Stéphane, Kouadio Assandé Moise, Koné Mamadou Guy-Richard, Yves Kily Hervé Fagnidi & Soro Doh · Asian Journal of Chemical Sciences · 2025

Malaria, although a curable disease, continues to be the most important infectious disease in terms of incidence and mortality worldwide. It is a potentially fatal disease caused by parasites transmitted to people through the bites of infected female Anopheles mosquitoes. This di...

Open access Research Article 10.9734/ajocs/2025/v15i1352