Shwetha Gopal, Zainab Imtiaz, Olumide Ijishakin, Olusayo Louise-Oluwasanmi, Helen Surafeal Berhe, Ogunniyi Kayode Emmanuel, Efe Oni, Gift Joanna Agbo, Kareeba Leefoon Gabriel, Victor Chiedozie Ezeamii, Janet Omole, Efe Okunzuwa, Aaquib Syed Amiruddin, Omolola Okunromade & Lakshmi Tulasi Rayapati·Journal of Advances in Medicine and Medical Research·2023
Background: Cardiomyopathies represent a heterogeneous group of heart muscle diseases with diverse etiologies. With the advent of molecular biology and genetic engineering, novel therapeutic strategies are being developed and explored to target the genetic basis of these diseases...
Open access
Research Article10.9734/jammr/2023/v35i225244
Maryam Abbas, Olumide Ijishakin, Shwetha Gopal, Iqra Saeed, Shilpa Arcot, Chidera Emmanuel Okezie, Gift Joanna Agbo, Victor Chiedozie Ezeamii, Omobolaji Samuel Ajayi, Ngozi Amanze, Sadam Alzaki, Tambi Isaac, Husna Shahnoor, Efe Okunzuwa & Amy Alfy·Journal of Advances in Medicine and Medical Research·2023
Calprotectin (CLP) comprises two calcium-binding proteins from the S-100 protein family, S100A8 and S100A9. CLP involves various cellular processes in lung health and disease, including anti-microbial functions, pro- and anti-tumor properties, angiogenesis, DNA damage response, a...
Open access
Research Article10.9734/jammr/2023/v35i225265
Zainab Imtiaz, Filagot D Eshete, Laaraib Arshad, Shwetha Gopal, Muhammad Najmal Qamar Siddiqui, Tope Mwuese Anyiman, Oluwatoyin Ayo-Farai, Terwase Anyiman, Obianyo Chekwube Martin, Ome Valentina Akpughe, Henry Onyemarim, Abdeltawwab Ahmed, Kareeba Leefoon Gabriel, Victor Chiedozie Ezeamii & Nicole Leonie Ho-Sang·Journal of Advances in Medicine and Medical Research·2024
Background: Sodium-glucose cotransporter-2 (SGLT2) inhibitors have recently drawn attention as a viable therapy for acute heart failure (AHF). Despite this, a comprehensive synthesis of current research has not been undertaken. Methods: Following the Preferred Reporting Items for...
Open access
Research Article10.9734/jammr/2024/v36i15349
Shaheen Sultana, Kayode Aguda, Adetola Mowo-wale, Regina Azipu, Chiedozie Steven Nzotta, Sadam Abualbshr Mohammed Alzaki, Marian Obi, Onyinye Ezewudo, Abdelhay Hassan Taha Mohamed, Shwetha Gopal, Tope Mwuese Anyiman, Ngozika Grace Obiefuna, Efi Uyoyou Winners, Omolola Okunromade, Prince Agbakahi & Jovita Echere·Journal of Advances in Medicine and Medical Research·2024
Background: Hypertension is a global health challenge, affecting over a billion individuals worldwide. Despite the availability of effective treatments, control rates remain suboptimal. Emerging technologies, such as smartphone applications, offer new avenues to enhance hypertens...
Open access
Research Article10.9734/jammr/2024/v36i85522
Kibrom Hailemariam Mesfin, Marian Onyinyechi Obi, Mayowa Nene Odugunwa, Maryfortune Ugoeze Chilaka, Roshan Goswami, Mary Iwuagwu, Akash Ajaykumar Mendha, Isabella Vittorino Mejia, Norense Ehimwenma, Kayode Aguda, Shwetha Gopal, Oghenerukevwe Faith Ohwodo, Fracia Wanjiku Waithaka, Onyinye Ezewudo, Regina Azipu & Jovita Echere·Journal of Advances in Medicine and Medical Research·2024
Acute coronary syndrome (ACS) remains a leading cause of morbidity and mortality worldwide. The accumulation of platelets is central to the development and pathogenesis of ACS, making antiplatelet therapy a cornerstone in its management. This review aims to assess the effectivene...
Open access
Research Article10.9734/jammr/2024/v36i95555
Kelechi Adannaya Iwuji, Hla Thwe, Olabisi Basirat Akinsanya, Eden Firew, Oluwatobi Atiba, Cindy Onumajuru, Huma Irfan, Saria Qaiser, Uzoamaka Amara Ogbu, Nahid Ahmed Abdelhadi, Chidinma Chijioke, Shwetha Gopal, Ogochukwu Ekpeleamaka Chioma, Abiola Yetunde Oyesile, Jyothsna Goranti & Jovita Echere·Journal of Advances in Medicine and Medical Research·2025
Background: In recent years, there has been growing interest in the potential role of corticosteroids as adjunctive therapy in severe. Community-acquired pneumonia (CAP) cases. It is a significant global health burden, contributing substantially to infectious disease-related morb...
Open access
Research Article10.9734/jammr/2025/v37i85903
Ayesha Taqi, Oluwamayomikun Soremekun, Mayowa Nene Odugunwa, Tope Mwuese Anyiman, Olumide Ijishakin, Victor Chiedozie Ezeamii, Chidera Emmanuel Okezie, Hassan Muhammed Ul Haq, Tiwalade O. Ogunlaja, Ngozi Amanze, Saeed Razaq, Shwetha Gopal, Kibrom Hailemariam Mesfin, Chijioke Okonkwo & Khudija Nayab·Journal of Advances in Medicine and Medical Research·2023
Background: Antibiotic-resistant infections pose a significant challenge to global health, and innovative solutions are urgently needed. Phage therapy, the therapeutic use of bacteriophages to treat bacterial infections, has been suggested as a potential alternative to antibiotic...
Open access
Research Article10.9734/jammr/2023/v35i235289
Tobechukwu Chinenye Ezike, Tania M. Cobena Bravo, Roshan Goswami, Luis Fernando Jimenez Cepeda, Huma Irfan, Tagbo Ejike Onyemelukwe, Maryfortune Ugoeze Chilaka, Ibiai Stephanie Lolomari, Vimla Devi, Sefiyah Lawal, Chukwuma Chuma-Eze, Oluwatobi Bamikole Opeyemi, Shwetha Gopal, Agho Osamede & Peace Divine Akhimienmhona·Journal of Advances in Medicine and Medical Research·2025
Background: Primary Biliary Cholangitis (PBC) is a chronic autoimmune liver disease characterised by progressive bile duct destruction, leading to liver failure if untreated. While ursodeoxycholic acid (UDCA) is the first-line therapy for PBC, 30-40% of patients exhibit an incomp...
Open access
Research Article10.9734/jammr/2025/v37i55829
Stephanie M. Brown, Hla Myo Thwe, Roshan Goswami, Tania M. Cobena Bravo, Ademilua Oluwatobi Iyanuoluwa, Frederick Ferguson, Maryfortune Ugoeze Chilaka, Shaheen Sultana, Shazia Noreen Durrani, Ayodele Paul Ogunro, Kayode Aguda, Regina Azipu, Onyinye Ezewudo, Ngozika Grace Obiefuna, Shwetha Gopal & Jovita Echere·Journal of Advances in Medicine and Medical Research·2024
Background: The co-occurrence of acute respiratory distress syndrome (ARDS) and sepsis presents a critical challenge in critical care medicine. ARDS involves diffuse alveolar damage, leading to severe hypoxemia, while sepsis entails a dysregulated host response to infection, resu...
Open access
Research Article10.9734/jammr/2024/v36i105584
Jovita Echere, George Sayegh, Felix Asaju, Eke Nwanne Okafor, Oluwaseun Abayomi Oguntuase, Armelle Jordan Leukeu, Elijah Oluwasegun Ayoigbala Adetunji, Omar Badr, Stephanie M. Brown, Shaheen Sultana, Regina Azipu, Onyinye Ezewudo, Marian Obi, Frederick Ferguson & Shwetha Gopal·Journal of Advances in Medicine and Medical Research·2024
Background: The ability to predict clinical outcomes in Non-ST Segment Elevation Myocardial Infarction (NSTEMI) could potentially lead to better risk stratification and treatment management. This systematic review aims to evaluate the predictive value of systemic biomarkers on th...
Open access
Research Article10.9734/jammr/2024/v36i95556