Shuning Hu

Development of a Three-dimensional Gel Culture Model of Caenorhabditis elegans Muscular Atrophy Induced by Acoustic Levitation Simulating Microgravity

Shuning Hu, Zherong Yu, Qingyu Xiong, Ke Zhang & Chun Chen · Annual Research & Review in Biology · 2025

Aims: This study aimed to establish an acoustic levitation-based microgravity simulation model and investigate its effects on the locomotor function and muscle protein expression of Caenorhabditis elegans. Methodology: L4-stage N2 nematodes were assessed on gel ball and on cultur...

Open access Research Article 10.9734/arrb/2025/v40i52239

Physiological Indicators of Paeoniflorin and Caffeine in Modulating the Motility of Caenorhabditis elegans Via Adenosine Receptor

Wenjie Nie, Shuning Hu, Sudan Ye & Chun Chen · Annual Research & Review in Biology · 2025

Aims: Paeoniflorin exhibits a broad range of in vitro and in vivo pharmacological effects. However, its potential as a drug targeting adenosine receptors remains largely unexplored. Methodology: In this study, the wild-type N2 strain and the Ador-1 gene knockout EG6890 strain of...

Open access Research Article 10.9734/arrb/2025/v40i42219

Physiological Indicators of Adenosine and Salidroside Regulating the Motor Behavior in a Caenorhabditis elegans Model Via Ador-1 Adenosine Receptor

Yingcheng Yang, Shuning Hu, Sudan Ye & Chun Chen · Annual Research & Review in Biology · 2025

Aims: Adenosine and salidroside exert both preventive and therapeutic effects on neurodegenerative diseases, including Alzheimer's and Parkinson's diseases. However, the mechanism is unclear. Methodology: N2 wild-type and EG6890 (Ador-1 gene knockout) Caenorhabditis elegans were...

Open access Research Article 10.9734/arrb/2025/v40i32211