Room Temperature Na2CO3-Catalysed One-pot Reaction of Benzaldehydes, Malononitrile and Phloroglucinol in Water, a Simple Green Synthetic Route to Antibacterial 2-Amino-4H-Benzopyrans
Ishmael B. Masesane & Shetonde O. Mihigo · International Research Journal of Pure and Applied Chemistry · 2015
A simple and green room temperature Na2CO3-catalysed three-component reaction of benzaldehydes, malononitrile and phloroglucinol in water to give 2-amino-4H-benzopyrans in 70-96% yields is described. The reaction was tolerated by electron-donating and electron-withdrawing substit...
Open access
Research Article
10.9734/IRJPAC/2015/20066