Sharath T P

Innovative Superdisintegrant Strategy for the Formulation of Rapidly Disintegrating Lamotrigine Tablets

Ramakrishnasai N, Sharath T P, Narahari K V, Naga mownica K P, Lakshmi Priya N S, Shrikrishna M Naik & Sagar M · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aims: Lamotrigine (LMG) is a poorly water-soluble antiepileptic drug (0.17 mg/mL at 25°C), commonly prescribed for epilepsy, including secondary generalized tonic-clonic seizures, as well as simple and complex partial seizures. Due to its low solubility and swallowing difficulty...

Open access Research Article 10.9734/jamps/2025/v27i5783

Optimized Nanosponges for Topical Delivery of Posaconazole: A Promising Approach for Enhanced Antifungal Therapy

Shrikrishna M Naik, Anasuya Patil, Taaniya Javalkar, Sharath T P & Yashwanth S · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2025

Aim: To enhance the topical delivery of posaconazole (PCZ) through the development of a nanosponge-based hydrogel system. Objective: To formulate and evaluate a Carbopol 934-based hydrogel containing optimized nanosponge (F6) for improved drug encapsulation, sustained release, an...

Open access Research Article 10.9734/ajrimps/2025/v14i2311

Unleashing the Potential of Spanlastics as Drug Delivery Carrier

Lakshmi Priya N S, Shivakumar Hagalavadi Nanjappa, Narahari K V, Arpitha Nandakumar, Sharath T P & Yashwanth S · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Spanlastics, a novel class of vesicular drug delivery systems, have garnered significant attention for their potential to overcome the limitations of traditional drug administration. Comprising non-ionic surfactants and edge activators, spanlastics exhibit unique characteristics...

Open access Research Article 10.9734/jamps/2025/v27i5776