Shakhnoz Azimova

Study of the Biological Activity of Alkyl Derivatives of Tetrahydroisoquinolines

Umida Khamidova, Ekaterina Terenteva, Mukaddas Umarova, Jaloliddin Abdurakhmanov, Sabirdjan Sasmakov, Artyom Makhnyov, Valentina Vinogradova, Abdusalom Saidov, Zaynat Khashimova & Shakhnoz Azimova · Journal of Pharmaceutical Research International · 2021

A row of 1-alkyne (C6-C17) derivatives against tetrahydroisoquinoline have been synthesized. 1-alkyne (C6-C17) derivatives cytotoxicity against three lines of cancer cells and two lines of normal cells was studied. It was found that 1-tridecyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoq...

Open access Research Article 10.9734/jpri/2021/v33i46B32938

The Use of Different Proteins as a Carrier Protein to Obtaining Morphine-Protein Conjugates for ELISA Diagnosis of Drug Addicts

Farkhod Eshboev, Elvira Yusupova, Galina Piyakina, Sabirdjan Sasmakov, Jaloliddin Abdurakhmanov, Shuhrat Khasanоv, Oybek Ashirov, Sherali Kuziev, Durdona Toshpulatova & Shakhnoz Azimova · Journal of Pharmaceutical Research International · 2021

Drug addiction is one of the biggest problems of medicine because diagnosis and treatment of drug addiction are difficult compared with some other socially significant diseases. In this study, synthesis and evaluation of four carrier protein-morphine conjugates were experimented....

Open access Research Article 10.9734/jpri/2021/v33i46B32943