The Efficacy of Tramadol Combined with A Donor of NO, Glyceryl Trinitrate (GTN) Mixture on Cytokines, NF-KB Expression and Oxıdative Stress Marker in the Rat Model of Formalin-Induced Inflammation
Selda Sen, Firuzan Kacar Doger, Mustafa Ogurlu, Osman N Aydın, Zerrin Akcal, Serdar Şen & Aslıhan Karul · Journal of Advances in Medicine and Medical Research · 2013
In addition to well-known analgesic action of tramadol, its potential antinflammatory effects have not been thoroughly evaluated. On the other hand, effectiveness of antioxidants is also reported against inflammation. It is known that glyceryl trinitrate, as a nitric oxide donor,...
Open access
Research Article
10.9734/BJMMR/2013/4410