Aims: Two simple and sensitive stability- indicating methods were developed and validated for the quantitative determination of sofosbuvir in presence of its degradation products. Study Design: Ultra high performance liquid chromatography (UPLC), High performance thin layer chrom...
Open access
Research Article10.9734/ajacr/2019/v3i430097
Rosuvastatin-Ca was prepared in solid dispersion as buccoadhesive tablets to increase its bioavailability and the release of the drug from its buccoadhesive formulae due to its poor aqueous solubility. The solid dispersions were prepared using β-cyclodextrin, polyethylene glycol...
Open access
Research Article10.9734/BJPR/2014/9257
Three new accurate and sensitive methods were developed for the determination of two veterinary drugs. Florfenicol was analyzed by a stability-indicating TLC/densitometric method in presence of its amine degradation product obtained via acid hydrolysis. It was based on the differ...
Open access
Research Article10.9734/BJPR/2014/6495
Aims: Stability indicating densitometry-TLC assay was established and validated for determination of azelastine hydrochloride (AZT) and emedastine difumarate (ETD) in the presence of their acid and oxidative degradants. Methodology: Forced degradation was performed using 30% H2O2...
Open access
Research Article10.9734/BJPR/2014/3693
Aims: Two spectrophotometric methods were developed and validated for the determination of sofosbuvir in presence of its alkaline degradate. Study Design: Ratio difference and ratio derivative methods were assisted for determination of sofosbuvir in presence of its alkaline degra...
Open access
Research Article10.9734/ajacr/2020/v5i230129
Aims: To develop methods with complete validation according to ICH guidelines and to be applied for the determination of avanafil in pure form and in pharmaceutical formulation in the presence of its degradation products. Study Design: High performance thin layer chromatography (...
Open access
Research Article10.9734/ajocs/2019/v6i419005