Background: Paclitaxel-induced painful neuropathy is a major dose-limiting side effect and can persist for up to two years after completing treatment that greatly affects both the course of chemotherapy and quality of life in cancer patients. Peroxisome proliferator-activated rec...
Open access
Research Article10.9734/jpri/2021/v33i38B32112
Diabetes mellitus (DM) is one of the most common causes and comorbidities in chronic kidney disease (CKD) globally. Particularly, DM in CKD patients increases the overall risk for kidney failure, atherosclerotic cardiovascular disease, heart failure, and premature mortality. Rece...
Open access
Research Article10.9734/ajrn/2026/v9i1125
Chronic kidney disease (CKD) is one of the leading causes of death. It is characterized by progressive decline in glomerular filtration rate (GFR), irreversible structural and functional kidney damage often associated with co-morbidities and multiple complications, including hype...
Open access
Research Article10.9734/ijanr/2026/v9i197
The maneuver clinical investigation of an effective drug for coronavirus disease 2019 (COVID-19) is still ongoing and the milieu of a successful investigational drug with proven efficacy is still obscure. Drug repurposing is a method to identify new therapeutic uses for existing...
Open access
Research Article10.9734/jamps/2023/v25i11653
Tetracyclines are broad-spectrum antibiotics effective against a wide variety of microorganisms including bacteria, both Gram-positive and Gram-negative, mycoplasmas, rickettsiae, chlamydiae, and protozoan parasites. Owing to their broad-spectrum antimicrobial activities and inex...
Open access
Research Article10.9734/ajrid/2023/v13i4271
Background: Surgical site infections are a prevalent cause of nosocomial infections that require antibiotic prophylaxis. Emergence and spread of antimicrobial resistance is a major global public health issue that must be addressed. Eventually, antibiotic prescribing pattern shoul...
Open access
Research Article10.9734/jpri/2021/v33i41B32339
Background: Neuropathic pain is a chronic incapacitating painful condition for which there is no effective treatment. The peroxisome proliferator-activated receptors (PPARs) are ligand-activated nuclear transcription factors that play key roles in modulating immune and inflammato...
Open access
Research Article10.9734/jpri/2021/v33i39B32176
Background: Bacteria have ability to rapidly evolve, develop strategies to resist antibiotics, and reduce the effectiveness of antibiotics. The emergence and spread of antimicrobial resistance is an important global public health challenge to tackle. Studying antibiotic prescribi...
Open access
Research Article10.9734/jpri/2021/v33i37A31980