Design, Synthesis and Biological Investigation of Some Novel Quinazolin-4(3H)-One Tethered 1, 3, 4-Thiadiazole-Thiol Motifs as Direct Enoyl Acyl Carrier Protein Reductase Inhibitors
Anant Deshpande, Shashikant Dhawale, Sanjaykumar Bari & Chandrakant Bonde · Journal of Pharmaceutical Research International · 2021
Aims: In this study was two noteworthy pharmacophores quinazolin-4(3H)-one and 1,3,4-thiadiazole through methylene bridge were utilized to design, synthesize and characterize some novel 2-methyl quinazolin-4(3H)-one and 6-chloro-2-methyl quinazolin-4(3H)-one tethered S-substitute...
Open access
Research Article
10.9734/jpri/2021/v33i47A33052