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Samuel Nzube Nwosu

Publications (7)

Advances in Anticancer Drug Discovery: Exploring the Untapped Potential of Natural Products for Targeted Therapies

Samuel Nzube Nwosu, Oluwabunmi Victoria Obagbemisoye, Christian Otitodilichukwu Onuba & Suliat Eniola Balogun · Journal of Advances in Medical and Pharmaceutical Sciences · 2024

Natural products have long been a significant source of structurally diverse and biologically active compounds, making them important for anticancer drug development. Taxol, a natural product isolated from the bark of the Pacific yew tree, is used to treat some cancers; Vincristi...

Open access Research Article 10.9734/jamps/2024/v26i11721

Tannin Extraction and Analysis in Telfairia occidentalis Seeds: A TLC and UV-based Approach

Samuel Nzube Nwosu, Anthony Godswill Imolele, Zubair Rofeeah Opeyemi, Daniel Anuoluwapo Olarewaju, Nwajiaku Godian Chidozie & Caleb Enejoh Omede · Asian Journal of Medical Principles and Clinical Practice · 2024

In this study, we extracted tannins from Telfairia occidentalis seeds and identified them using thin layer chromatography (TLC) in conjunction with ultraviolet (UV) analysis. We employed the "spot matching" technique to obtain numerical values, tallied, and represented them. TLC...

Open access Research Article

Revolutionizing Drug Discovery: The Impact of Artificial Intelligence on Efficiency and Accuracy

Samuel Nzube Nwosu · Journal of Advances in Medical and Pharmaceutical Sciences · 2024

This study explores the transformative impact of Artificial Intelligence (AI) techniques, such as machine learning and deep learning, on drug discovery. It highlights the roles of Al in enhancing efficiency and precision, accelerating processes, refining outcomes, and managing la...

Open access Research Article 10.9734/jamps/2024/v26i6695

Characterization and Preliminary Structural Elucidation of Flavonoids in the Seed of Telfairia occidentalis

Samuel Nzube Nwosu · Asian Journal of Medical Principles and Clinical Practice · 2024

Flavonoids are a group of plant compounds with a potential health benefits, including ant-oxidant, anti-inflammatory, and anti-carcinogenic properties. This study aimed to characterize the flavonoids in the seed of Telfaria Occidentalis using thin-layer chromatography (TLC) and U...

Open access Research Article

Implementation of Antimicrobial Stewardship (AMS): An Imperative Step to Reducing Resistance and Improving Infectious Disease Cure Rates

Emmanuel Ebuka Abonyi, Uyiose Fortress Ufuah, Samuel Nzube Nwosu & Favour Chidera Jonathan · Asian Journal of Medical Principles and Clinical Practice · 2022

The discovery of penicillin in 1940 by Alexandra Fleming brought a major breakthrough in the management of infectious diseases and further sparked special interest in the research and development of antimicrobial agents. However, in a matter of time, penicillin like the sulphonam...

Open access Research Article

The Impact of Antimicrobial Resistance on Cancer Treatment: A Systematic Review of Current Evidence and Future Directions

Olabisi Promise Lawal, Nurain Kehinde Ahmed, Taiwo Ayomide Ilesanmi, Godswill Imolele Anthony, Samuel Nzube Nwosu, Festus Oladayo Ogungbemiro, Zainab Olaide, Muritadoh Muritadoh Adeniyi, Uchechukwu Lilian Okoye, Adebiyi Mutiat Olufunmilayo, Adegbesan Abiodun Christopher & Ikalo David Oseghale · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2024

Background: Antimicrobial resistance (AMR) has emerged as a critical global challenge, posing substantial implications for managing infectious diseases and impacting treatment efficacy across diverse medical conditions, including cancer. Cancer patients are often susceptible to b...

Open access Research Article 10.9734/ajrimps/2024/v13i4270

Proximate Analysis, Extraction, and Characterization of Oil from Terminalia catappa Fruit in Anambra State, Nigeria

Aniekwensi Obinna Patrick, Ogbonna Esther Ozioma, Gemadi Kwasi Shine, Akinpelu Toyosi Michael, Samuel Nzube Nwosu, Etim Blessing Bassey, Nwachukwu Chinemerem Favour, Awoyungbo Modupeoluwa Damilola & Nkwocha Stephen Tochi · Asian Journal of Research in Biochemistry · 2024

Context: Terminalia catappa, also known as tropical almond, is a well-known plant recognized for its edible parts, including fruit, bark, leaves, and roots. It is also noted for its medicinal usefulness and numerous pharmacological actions. Aim: This study aims to analyze the pro...

Open access Research Article 10.9734/ajrb/2024/v14i4301