Esmethadone in Major Depressive Disorder: Pharmacology and Clinical Evidence
Olaniyi David Ogundeji, Nkechinyere M Harry, Akinyemi Akinwumiju, Obianuju Nwauwa, Gibson Anugwom & Samuel Nwaobi · Journal of Advances in Medicine and Medical Research · 2025
Major Depressive Disorder (MDD) affects approximately 280 million people globally, with current treatments showing significant limitations, including delayed onset of action, low remission rates, and troublesome side effects. Esmethadone (REL-1017, d-methadone) has emerged as a p...
Open access
Research Article
10.9734/jammr/2025/v37i85919