Samson O. Paulinus

Lipid Peroxidation and Glutathione Level Following Scopolamine-Induced Cognitive Dysfunction in Rats: Potentials of Telfairia occidentalis Seeds and Talinium triangulare Leaves Aqueous Extracts

Samson O. Paulinus, Eru M. Eru, Gabriel U. Udo-affah, Michael E. Oku, Ifiok Bassey, Kelechi C. Uruakpa, Nsikak M. Umoh, Michael Ajen, Sadeyeng E. Anani & Anozeng O. Igiri · Asian Journal of Research and Reports in Neurology · 2024

Background: Oxidative stress augmented with progressive age, causes changes in mitochondrial DNA, mitochondrial disruption and more oxidative trouble. This process is facilitated in Alzheimer’s disease by the pathology of αβ amyloid and activated microglia. Objectives: The presen...

Open access Research Article

Enhanced Effect of Aqueous Extract of Telfairia occidentalis Seed on the Microstructure of the Hippocampus of Scopolamine Hydrobromide-Induced Cognitive Dysfunction Rats

Eru M. Eru, Samson O. Paulinus, Anozeng O. Igiri & Mfon I. Akpaso · Asian Journal of Research and Reports in Neurology · 2020

Aims: This study assessed histological parameter of the hippocampus using scopolamine-induced cognitive dysfunction rats following the administration of aqueous extract of Telfairia occidentalis seed. Materials and Methods: Thirty Wistar rats weighed between 180-200 g were random...

Open access Research Article

Effect of Alkaloid-rich Fraction of Dacryodes edulis Leaves on the Microstructure of the Hippocampus and Blood Glucose Levels of STZ-Induced Diabetic Wistar Rats

Eru, E.M, Theresa I. Ekpenyong, Cyril A. Agbor, Christie E. Fischer, Michael E. Oku, Samson O. Paulinus, Etim D. Isaiah, Kelechi C. Uruakpa, Williams A. Nnenna, Nsikak M. Umoh, Eric A. Agaba & Anozeng O. Igiri · International Neuropsychiatric Disease Journal · 2025

Aim: the aim of this study was to elucidate the effect of alkaloid-rich fraction of Dacryodes edulis on body weight, blood glucose level and the microanatomy of the hippocampus of STZ-induced Diabetic Wistar rats. Methodology: 25 adult male Wistar rats were used for the experimen...

Open access Research Article 10.9734/indj/2025/v22i3477