Sameera R. Samarakoon

Screening of Fifteen Mangrove Plants Found in Sri Lanka for in-vitro Cytotoxic Properties on Breast (MCF-7) and Hepatocellular Carcinoma (HepG2) Cells

Sameera R. Samarakoon, Chanthirika Shanmuganathan, Meran K. Ediriweera, Poorna Piyathilaka, Kamani H. Tennekoon & Ira Thabrew · European Journal of Medicinal Plants · 2016

Aims: Evaluation of cytotoxic potential on the leaves and stem bark extracts of 15 mangrove plants grown in Sri Lanka on breast cancer (MCF -7) and hepatocellular carcinoma (HepG2) cells. Place and Duration of Study: At the Institute of Biochemistry, Molecular Biology and Biotech...

Open access Research Article 10.9734/EJMP/2016/26107

Evaluation of Selected Natural Compounds for Cancer Stem Cells Targeted Anti-cancer Activity: A Molecular Docking Study

Karthika Mayan, Sameera R. Samarakoon, Kamani H. Tennekoon, Asitha Siriwardana & José R. Valverde · European Journal of Medicinal Plants · 2016

Aims: Cancer stem cells (CSCs) play significant roles in tumor initiation, relapse, angiogenesis, metastasis and therapy. Collectively Wnt, Notch, and Hedgehog are major pathways that have been linked to the drug resistance of CSCs. Eliminating CSCs has been suggested as a promis...

Open access Research Article 10.9734/EJMP/2016/27847

Cytotoxic, Antioxidant and Apoptotic Effects of Twenty Sri Lankan Endemic Plants in Breast Cancer Cells

Panchima P. Jayarathna, Kamani H. Tennekoon, Sameera R. Samarakoon, Ira Thabrew, Eric H. Karunanayake, E. Dilip de Silva & Meran K. Ediriweera · European Journal of Medicinal Plants · 2016

Aims: Main aim of this study was to evaluate cytotoxic, antioxidant and apoptotic properties of Sri Lankan endemic plants in estrogen receptor positive (MCF-7) breast cancer and triple negative breast cancer (MDA-MB-231) cells. Place and Duration of Study: At the Institute of Bio...

Open access Research Article 10.9734/EJMP/2016/26591