Safiah Alhazmi

The Role of Immune-related NLR Pyrin Domain Containing 2 (NLRP2) Gene in the Development and Diseases

Fatemah Basingab, Asmaa Alghamdi, Safiah Alhazmi, Aisha Alrofaidi & Mona Alharbi · Journal of Pharmaceutical Research International · 2021

The Nucleotide-binding oligomerization domain, Leucine-rich Repeat, and Pyrin domain-containing (NLRP) family, including NLR Family Pyrin Domain-Containing 2 (NLRP2) gene, is defined as a critical element in regulating both apoptosis and inflammation. Although the NLRP2 protein i...

Open access Research Article 10.9734/jpri/2021/v33i1831312

The Role of Alpha-1-acid Glycoprotein 2 Protein and the Underlying Orosomucoid 2 Gene in Different Diseases

Khulood Alotaibi, Alaa Mufawwaz, Mona Alharbi, Jehan Alrahimi, Fatemah Basingab & Safiah Alhazmi · Journal of Pharmaceutical Research International · 2022

Alpha-1-Acid glycoprotein 2 (AGP2) or orosomucoid 2 (ORM2) is a major plasma protein. AGP2 is a member of the immunocalin family, a lipocalin subfamily expressed mainly in hepatocytes and also in astrocytes and endothelial cells. The detailed physiological role of this protein ha...

Open access Research Article 10.9734/jpri/2022/v34i20A35821

The Correlation between Gene Expression and DNA Methylation Levels of RAS p21 Protein Activator 3 (RASA3) Gene in Saudi Autistic Children

Aisha Alrofaidi, Rawan Saeed Alghamdi, Mona Alharbi, Khloud Algothmi, Reem Farsi, Najla Alburae, Magdah Ganash, Fatemah Basingab, Sheren Azhari, Heba Alkhatabi, Aisha Elaimi, Manal Shaabad, Ashraf Dallol, Amany Alqosaibi, Mohammed Jan, Hesham Aldhalaan & Safiah Alhazmi · Journal of Pharmaceutical Research International · 2021

The potential role of DNA methylation pattern in autism has been provided by revealing the differences in methylation level of multiple genes which are significantly associated with their expression and implicated in ASD pathogenesis. RASA3 is a member of GTPase-activating protei...

Open access Research Article 10.9734/jpri/2021/v33i33B31794