Background: Systemic lupus erythematosus (SLE) with onset after the age of 50 years accounts for approximately 10–20% of cases and is often associated with atypical clinical features and delayed diagnosis. Gastrointestinal involvement as an initial manifestation is uncommon, and...
Open access
Research Article10.9734/ajrrga/2026/v9i1214
Background: Golimumab, a human monoclonal antibody targeting tumor necrosis factor-alpha (TNF-α), is widely used to treat ankylosing spondylitis (AS). However, it can paradoxically trigger dermatological conditions, including psoriasis. This report details a rare instance of palm...
Open access
Research Article10.9734/ajcrmh/2025/v8i1237
Werner syndrome (WS), or adult progeria, is a rare autosomal recessive disorder characterized by premature aging and multisystem involvement. Its initial presentation through a metabolic emergency remains exceptional. We report the case of a 41-year-old woman with a history of ch...
Open access
Research Article10.9734/ajcrmh/2025/v8i1230
Background: Thrombotic microangiopathy (TMA) is a rare but severe manifestation of systemic lupus erythematosus (SLE), frequently associated with antiphospholipid syndrome (APS). Early recognition is crucial, as it significantly influences renal and overall prognosis (George &...
Open access
Research Article10.9734/ajcrmh/2026/v9i1315
Behçet’s disease (BD) is a rare systemic vasculitis with an unclear etiology, infrequently associated with hematologic malignancies. We report a 27-year-old man with severe mucocutaneous BD who developed acute myeloblastic leukemia (AML-1) following a SARS-CoV-2 infection. The pa...
Open access
Research Article10.9734/ajcrmh/2025/v8i1234
We report a rare association of Late Onset Combined Immunodeficiency (LOCID) with epidermodysplasia verruciformis (EV) in a 23-year-old Moroccan woman. At age 7, the patient developed thousands of small verrucae and experienced recurrent respiratory and gastrointestinal infection...
Open access
Research Article10.9734/ajcrmh/2025/v8i1228
Relapsing polychondritis (RP) is a rare, immune-mediated systemic disorder with an estimated prevalence of 4.5 to 20 cases per million population. It is characterized by recurrent inflammation of cartilaginous and proteoglycan-rich tissues, particularly affecting the auricles, na...
Open access
Research Article10.9734/ajcrmh/2025/v8i1224