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S. Parimala Krishnan

Publications (6)

Optimization of Site-Specific Drug Delivery System of Tyrosine Kinase Inhibitor Using Response Surface Methodology

S. Parimala Krishnan, Cinnayyagari Mahesh Reddy & Challa Balashekar Reddy · Journal of Pharmaceutical Research International · 2021

Aims: The aim of present study was to develop a stomach specific formulation of Imatinibmesylate to increase the fraction of drug absorbed in stomach. Study Design: Development and Optimization of Microspheres for site specific delivery.. Place and Duration of Study: The study wa...

Open access Research Article 10.9734/jpri/2021/v33i46B32941

A Mini-Review on Chitosan Microsphere Drug Delivery

Cinnayyagari Mahesh Reddy, S. Parimala Krishnan & Challa Balashekar Reddy · Journal of Pharmaceutical Research International · 2021

The study aims to determine the drug therapy of any disease to attain the desired therapeutic concentration of the drug in plasma or at the site of action and maintain it for the entire duration of treatment. A drug on being used in conventional dosage forms leads to unavoidable...

Open access Research Article 10.9734/jpri/2021/v33i49A33318

Vesicular and Stealth Vesicular Drug Delivery – A Review

Bandaru Lakshmi Narayana Rao, S. Parimala Krishnan & Challa Balashekar Reddy · Journal of Pharmaceutical Research International · 2021

Vesicular systems (liposomes), one of several potential novel drug delivery systems, provide an advanced technology for delivering active compounds to the site of action, and numerous formulations are currently in clinical use. Liposome technology has developed from typical vesic...

Open access Research Article 10.9734/jpri/2021/v33i47B33098

Application of Box–Behnken Design and Desirability Function in the Development and Optimization of Stealth Liposomes of Microtubule Inhibitor

Bandaru Lakshmi Narayana Rao, S. Parimala Krishnan & Challa Balashekar Reddy · Journal of Pharmaceutical Research International · 2021

Aims: The aim of the present study was to develop and optimize a Stealth Liposomal Drug Delivery System of microtubule inhibitor using Box–Behnken Design and Desirability function. Study Design: Development and Optimization of Stealth Liposomes. Place and Duration of Study: The s...

Open access Research Article 10.9734/jpri/2021/v33i47A33046

Drug Prescription Pattern of Psychotropic Drugs Used for the Management of Schizophrenia in a Tertiary Care Speciality Hospital in South Kerala

Dhanya Dharman, S. Parimala Krishnan & K. G. Ravikumar · Journal of Pharmaceutical Research International · 2021

An individual affected by psychotic illness is usually a burden to both the society as well as their family in terms of non-productivity. The WHO recognized the significance of mental health and defined it as “a state of complete physical, mental and social well-being”.A psychiat...

Open access Research Article 10.9734/jpri/2020/v32i4531094

Prevalence, Pattern and Monitoring of Adverse Drug Reaction in Tertiary Care Psychiatry Setting- A Hospital Based Study in South Kerala

Dhanya Dharman, S. Parimala Krishnan & K. G Ravikumar · Journal of Pharmaceutical Research International · 2021

Pharmacovigilance programs usually aim to gather information on the effect of prescribed drugs in the real world rather than in groups of short-lived and carefully selected clinical trial populations. Adverse drug reactions (ADR) associated with psychiatric medications may vary a...

Open access Research Article 10.9734/jpri/2020/v32i4231052