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S. C. Meludu

Publications (10)

Effect of a Three-Month Exercise Regime on Androgens and Sex Hormone-binding Globulin of Premenopausal Students of Nnamdi Azikiwe University, Nnewi, Nigeria

C. M. Njoku, S. C. Meludu, A. J. Onuegbu, M. J. Olisekodiaka, N. O. Osakue, C. C. Onyenekwe & E. N. Osakue · Asian Journal of Research and Reports in Endocrinology · 2026

Background: There is traditional conviction that if premenopausal women engage in prolonged physical exercise, they are likely to become masculinized and develop infertility. Androgens, although traditionally thought to be male sex steroids, play important roles in female reprodu...

Open access Research Article 10.9734/ajrre/2026/v9i1138

Blood Lipids and Its Atherogenic Indices in Alloxan Induced Diabetic Male Rats

O. D. Chikezie, S. C. Meludu, I. S. I. Ogbu, B. N. Egejuru, T. Ude & O. Ekuma-Ogbonnia · Asian Journal of Advanced Research and Reports · 2020

Background: Diabetes mellitus is a group of metabolic disorders which result to excessive accumulation of blood sugar over a prolonged period. Due to higher risk of diabetes mellitus to cardiovascular disease, it is crucial to identify and address these cardiovascular risks. This...

Open access Research Article 10.9734/ajarr/2020/v9i230216

Some Oxidative Biomarkers and Antioxidant Genes Detection in Diabetic Male Rats

O. D. Chikezie, S. C. Meludu, I. S. I. Ogbu, I. C. Maduka, T. Ude & B. N. Egejuru · Archives of Current Research International · 2020

Background: Diabetes mellitus is a group of metabolic disorder in which there are high blood sugar levels over a prolonged period. This study assessed the effects of diabetes on levels of some oxidative biomarkers and pattern of antioxidant genes expression in the peripheral bloo...

Open access Research Article 10.9734/acri/2020/v20i230173

Effect of Methanolic Extract of Ocimum gratissimum on Blood Pressure, Some Electrolytes, Renal and Cardiac Biomarkers in 8% NaCl Induced Hypertensive Male Wistar Rats

O. B. Onyema-iloh, S. C. Meludu, E. O. Iloh, C. E. Dioka, O. S. Usman, O. A. Onyegbule & E. B. Olugbenga · European Journal of Medicinal Plants · 2019

Background: Ocimum gratissimum (OG) is a shrub belonging to the family of Lamiaceae. It is commonly called scent leaf or clove basil and it is found in many tropical countries. Studies have shown that the leaf extract of Ocimum gratissimum possess medicinal properties. Aim: The e...

Open access Research Article 10.9734/EJMP/2018/45379

Effects of Methanolic Extract of Vernonia amygdalina on Electrolytes and Renal Biomarkers in NaCl – Induced Hypertensive Male Wistar Rats

O. B. Onyema-iloh, S. C. Meludu, E. O. Iloh, C. E.Dioka . & C. N. Obi-Ezeani · Journal of Pharmaceutical Research International · 2018

Vernonia amygdalina popularly called bitter leaf is used in traditional medicine to treat fever, malaria, diarrhoea, dysentery and diabetes. They serve as laxatives and fertility inducer. They are commonly used as vegetable. The effects of methanolic extract of Vernonia amygdalin...

Open access Research Article 10.9734/JPRI/2018/41908

The Dilemma of Exogenous Antioxidant Therapy in Clinical Practice in Nigeria: Insight into Health Implication

B. K. Myke-Mbata, S. C. Meludu & C. E. Dioka · Journal of Advances in Medicine and Medical Research · 2018

The growing interest among health care users in developing countries on antioxidant therapy has led to indiscriminate abuse of highly marketed antioxidant therapy. In a normal cell, there should be a balance of activities between free radicals and antioxidants which are tightly r...

Open access Research Article 10.9734/JAMMR/2018/39937

Antioxidant Supplementation and Free Radicals Quelling; the Pros and Cons

B. K. Myke-Mbata, S. C. Meludu & C. E. Dioka · Journal of Advances in Medicine and Medical Research · 2018

An antioxidant is a substance that inhibits oxidation of biomolecules by free radicals. Its primary role is to decrease or inhibit synthesis, scavenge and neutralise the effects of free radicals. A delicate balance is often maintained between antioxidant and free radical. Free ra...

Open access Research Article 10.9734/JAMMR/2018/39938

Moderately Increased Albuminuria; Marker of Chronic Complications in Nigerian Diabetes Mellitus Type 2 Patients; Makurdi Perspective

B. K. Myke-Mbata, S. C. Meludu, C. E. Dioka, S. A. Adebisi, E. K. Oghagbon, G. I. Achinge, C. E. Onah & B. O. Onyemailo · Journal of Advances in Medicine and Medical Research · 2015

Background: Diabetes mellitus (DM) and its complications are on the increase especially in the developing countries with significant negative economic consequences on individuals, families and health systems. Objective: We, therefore compared albumin/creatinine ratio, microalbumi...

Open access Research Article 10.9734/BJMMR/2015/18128

Effect of Ethanoic Extract of Gongronema latifolium Leaves on Malondialdehyde Level and Antioxidant Enzymes Activities in Tissue Samples of Streptozotocin Induced Diabetic Male Wistar Rats

R. A. Analike, J. E. Ahaneku, G. I. Ahaneku, D. L. Ajaghaku, S. C. Meludu, P. I. Ezeugwunne, C. E. Onah & E. C. Ogbodo · Asian Journal of Cardiology Research · 2022

Background/ Objective of Study: Diabetes mellitus continues to be a source of public health problem as a result of its major negative impact on the lives and well-being of individuals, families, and societies worldwide. The study evaluates the effect of ethanoic extract of Gongro...

Open access Research Article

Pattern of Serum Testosterone and Glycated Haemoglobin among Adult Males with Type 2 Diabetes Mellitus and Erectile Dysfunction Attending a Tertiary Hospital in South Eastern Nigeria

P. C. Obi, A. C. Anyanwu, C. B. Nwatu, N. Ekwueme, A. C. Mbaike, O. A. Onyegbule, A. C. Ihim, R. N. Oputa, C. Onah, F. O. Nwako, J. Nnodim, C. E. Dioka & S. C. Meludu · Journal of Advances in Medicine and Medical Research · 2016

Background: The global prevalence of diabetes mellitus (DM) is steadily increasing. Diabetes mellitus is associated with acute and chronic complications including erectile dysfunction (ED). Erectile dysfunction is commoner among men with diabetes mellitus than their non-diabetic...

Open access Research Article 10.9734/BJMMR/2016/28969