Background: The liver being the largest and central organ of nutrient metabolism is at a high risk of injury from the toxic metabolites of ingested materials. This invariably leads to rising incidence of chronic liver disease. This study investigated the ability of the aqueous ex...
Open access
Research Article10.9734/jocamr/2025/v26i8697
Background: Acute liver injury is a precursor of many chronic liver diseases which are of major global health burden. Chemicals including drugs, alcohol and psychoactive substances constitute major causes of acute liver injury. Methods: Varying degrees (mild, moderate and severe)...
Open access
Research Article10.9734/ajmah/2025/v23i41209
Cancer resistance to conventional therapies remains a significant challenge in oncology, leading to treatment failure and poor patient outcomes. Immunotherapy has emerged as a promising approach to overcome resistance by harnessing the body's immune system to recognize and elimin...
Open access
Research Article10.9734/aorj/2025/v8i197
Objective: The paired human kidneys are retroperitoneal organs responsible for the maintenance of the internal meliu of the human body. Chronic kidney disease is major cause of morbidity and mortality globally. Nutrition and life style are two main factors in the aetiopathogenesi...
Open access
Research Article10.9734/jamps/2023/v25i12659
Objective: Lead is a highly toxic, non-biodegradable heavy metal usually found in the environment largely as a pollutant of water, soil or air. Chronic lead exposure has adverse effects on human health. Lycopersicon esculentum has many phytochemicals that may ameliorate organ inj...
Open access
Research Article10.9734/jocamr/2023/v24i1489
Background: Keloids are exaggerated cutaneous scars with a preponderance of fibrous tissue that may complicate wound healing in people that are predisposed to its development. Its management could be challenging with very high probability of recurrence following surgical excision...
Open access
Research Article10.9734/jcti/2022/v12i3219
Objective: Drug induced liver injury is one of the sequelae of adverse drug reactions. We studied the efficacy of aqueous extract of Ocimum gratissimum at ameliorating carbon tetrachloride induced liver injury. Methodology: The study utilized five groups with six animals each. Li...
Open access
Research Article10.9734/jocamr/2022/v18i330354
Objective: In most human communities, the consumption of alcoholic beverages is unregulated with negative impact on health. The liver is one of the major organs that bear the brunt of regular and or heavy consumption of alcohol. This study set out to elucidate the modulation of a...
Open access
Research Article10.9734/ejmp/2022/v33i630470
Objective: The liver is the major organ of detoxification of ingested materials such as food, beverages and drugs, thus it is prone to toxicity with attendant pathologies. We studied the ability of Vitex agnus castus plant extract to ameliorate the biochemical and structural alte...
Open access
Research Article10.9734/ejmp/2021/v32i1030422
Background: Heamangioma constitutes the largest subset of vascular lesions. It is predominantly congenital with predilection for the head and neck region of the body but can involve any part or region of the body. The capillary variant may be post-traumatic. After initial prolife...
Open access
Research Article10.9734/jcti/2021/v11i330150
Objective: One of the debilitating complications of diabetes mellitus is chronic foot ulcer. Mangifera indica (Mango) is a naturally occurring and widely cultivated plant with many health benefits attributable to its parts. The wound healing potential of its bark in adult diabeti...
Open access
Research Article10.9734/jocamr/2020/v10i130152
Objective: The health hazards of tobacco smoking and diabetes mellitus constitute major and diverse global burden. The influence of Nicotiana tabacum (tobacco) powder and ethanolic extract on excised wound of diabetic rats was investigated. Methods: The wounds of diabetic adult m...
Open access
Research Article10.9734/jocamr/2020/v9i230139
Objective: One of the sequelae of diabetes mellitus is chronic foot ulcer. This study investigated wound healing propensity of the pulp and rind of Ananas comosus (a widely cultivated fruit with many health benefits) in diabetic wistar rats. Methods: The excisional wounds of twen...
Open access
Research Article10.9734/jocamr/2019/v7i330103
Introduction: Benign prostatic hyperplasia (BPH) afflicts about 90% of men in the 9th decade of life. Its management could pose socio-economic challenges. Citrullus lanatus is widely cultivated and known to have antioxidant properties that could impact positively on the managemen...
Open access
Research Article10.9734/EJMP/2016/25701
Aim: The efficacy of Telfairia occidentalis leaf and seed as herbal extracts in the management of induced benign prostatic hyperplasia (BPH) in Wistar rats was investigated. Methodology: Fifty adult male Wistar rats in 10 equal groups were utilized for the study. BPH was induced...
Open access
Research Article10.9734/EJMP/2016/22856
Aim: The wound healing ability of Carica papaya latex in excisional wound of alloxan induced diabetic wistar rats was investigated. Methodology: The excisional wounds of 24 diabetic rats in four equal groups were dressed respectively with latex (LD), gentamicin (GD), normal salin...
Open access
Research Article10.9734/EJMP/2015/17758
Background: Dyslipidemia is partly dependent on consumption of edible oils. We set out to determine the atherogenic effects of commonedible oils in Nigeria, in male Wistar rats and to find out if administration of oral kolaviron amelioratedthese effects. Methods: Forty-eight male...
Open access
Research Article10.9734/JPRI/2017/35360