Electronic Effect of Substituents Present on Carbonyl Compounds: Analysis of Product Formation in One-Pot Synthesis of 1, 3, 4-thiadiazole Ring
Sheetal B. Marganakop, Ravindra R. Kamble, Gangadhar Y. Meti & Mahadev N. Kumbar · Chemical Science International Journal · 2015
Functionalized N-(4-acetyl-5-substituted-4, 5-dihydro-[1, 3, 4]-thiadiazol-2-yl)-acetamides (2a-m) were synthesized by three-fold condensation of carbonyl compound, thiosemicarbazide and acetic anhydride in an one pot three component reaction. In this reaction substituents on c...
Open access
Research Article
10.9734/ACSJ/2015/18204