Ranjani Rajasekaran

SPARDA (Short Prokaryotic Argonaute, DNase-Associated): A CRISPR-Independent Prokaryotic Defense System with Emerging Biotechnological Potential

Ranjani Rajasekaran, Padmanath Krishnan, Saahithya Rajamohan & Sasikumar Sethuraman · Journal of Scientific Research and Reports · 2026

Microorganisms exist in environments densely populated by bacteriophages and mobile genetic elements, necessitating the evolution of sophisticated defense strategies. While CRISPR–Cas systems represent the best-characterized adaptive immune mechanisms in prokaryotes, recent genom...

Open access Research Article 10.9734/jsrr/2026/v32i64233

A First Case Report of Mannheimia haemolytica in Caprine Mastitis in Theni District of Tamil Nadu, India

Ranjani Rajasekaran, K. Padmanath, P. Suresh & S. Rathnapraba · Microbiology Research Journal International · 2025

Aim: To identify and assess the etiological agent responsible for caprine mastitis in a doe, analyse the antibiotic sensitivity and provide suitable treatment. Study Design: Clinical examination and microbiological analysis, followed by antibiotic sensitivity testing. Place and D...

Open access Research Article 10.9734/mrji/2025/v35i21544

In silico Analysis of Andrographolide, a Bioactive Compound of Andrographis paniculata, against the Androgen Receptor and Steroid 17-alpha-hydroxylase/17,20 Lyase as an Anti-prostate Cancer Agent

S. Sasikumar, Naveenkumar Viswanathan, Ranjani Rajasekaran, S. Tamilselvan, M. Sivakumar, R.Karthikeyan & Manju G Preedaa · Journal of Scientific Research and Reports · 2025

Prostate cancer incidence is high in male humans and male dogs. Increased male sex hormones play a vital role in pathogenesis. The treatment for prostate hyperplasia and prostate cancer is an androgen receptor inhibitor that inhibits the synthesis of androgen by blocking the enzy...

Open access Research Article 10.9734/jsrr/2025/v31i113738