R. Dushanan

Hydroxamic Acid Scaffolds as Metalloenzyme Inhibitors: Advances in Chemistry and Drug Discovery

R. Dushanan · Asian Journal of Chemical Sciences · 2025

Hydroxamic acids are among the most widely used metal-chelating pharmacophores in medicinal chemistry, with diverse applications ranging from oncology and infectious diseases to inflammation and parasitic infections. Their strong affinity toward Zn2+, Fe3+, Mn2+, and Mg2+ underli...

Open access Research Article 10.9734/ajocs/2025/v15i6413

Symphoxanthone and Celibixanthone as ACE2 Inhibitors against SARS-CoV-2 Using Molecular Docking, MM GBSA and Molecular Dynamics Studies

M.H.P. Dilhara, R. Dushanan & R. Senthilnithy · South Asian Research Journal of Natural Products · 2026

The COVID-19 pandemic posed an unprecedented global health challenge, leading to the rapid development of vaccines and antiviral drugs that substantially reduced disease-related mortality. Nevertheless, conventional synthetic drug discovery remains time-consuming and is often ass...

Open access Research Article 10.9734/sarjnp/2026/v9i1221