Influence of Alpha-thalassemia −3.7kb Mutation (αα/-α and -α/-α) upon Clinical Outcome of Homozygous Sickle Cell Disease
Siris Patel, Praveen K. Sahu & Preetinanda M. Dash · Asian Hematology Research Journal · 2022
Alpha thalassemia (α-thal), fetal haemoglobin (HbF) and beta-globin haplotype are considered classical genetic disease modifiers in Sickle cell disease (SCD) causing clinical heterogeneity. Nevertheless their impact on clinical emergence and disease progression is still elusive....
Open access
Research Article