The Antidepressant-like Effect of Hyperbrasilol B, A Natural Dimeric Phloroglucinol Derivative is Prevented by Veratrine, a Sensitive-Voltage Na+ Channel Opener
Fernanda Bossemeyer Centurião, Satchie Sakamoto, Ana Cristina Stein, Liz Girard Müller, Pietro Maria Chagas, Gilsane Von Poser, Cristina Wayne Nogueira & Stela Maris Kuze Rates · European Journal of Medicinal Plants · 2014
Aims: South Brazilian Hypericum species are a source of dimeric structures, constituted of filicinic acid and phloroglucinol moieties, which present antidepressant-like effects mediated by monoaminergic neurotransmission in rodents. Here, we show that hyperbrasilol B, a phloroglu...
Open access
Research Article
10.9734/EJMP/2014/7702