Padmanath Krishnan

SPARDA (Short Prokaryotic Argonaute, DNase-Associated): A CRISPR-Independent Prokaryotic Defense System with Emerging Biotechnological Potential

Ranjani Rajasekaran, Padmanath Krishnan, Saahithya Rajamohan & Sasikumar Sethuraman · Journal of Scientific Research and Reports · 2026

Microorganisms exist in environments densely populated by bacteriophages and mobile genetic elements, necessitating the evolution of sophisticated defense strategies. While CRISPR–Cas systems represent the best-characterized adaptive immune mechanisms in prokaryotes, recent genom...