The Relation between Glutathione S Transferase (GSTM1, GSTP1 and GSTT1) Polymorphisms and Clinical Diversity of Sickle Cell Disease among Pediatric Sudanese Patients
Naif Taleb Ali, Ozaz Yagoup Mohammed Ahmed, Fayad Osman Mohammed & Huda Mohammed Haroun · Asian Hematology Research Journal · 2021
Background: Sickle cell disease (SCD) is a highly variable condition, with some patients being asymptomatic and others frequently admitted to hospital. Impairment of the glutathione system due to genetic polymorphisms of glutathione S-transferase (GST) genes is expected to influe...