Oyewale Malik Tomilola

Integrated Virtual Screening of NPACT-Derived Phytochemicals as Potential FGFR1 Inhibitors for Cholangiocarcinoma Therapy: Molecular Docking, ADMET, MM-GBSA, and Molecular Dynamics

Atanda Opeyemi Emmanuel, Oyewale Malik Tomilola, Adeyeye Pius Oluwaseyi, Adesikun Aanu Adedamola & Adeyemi Mary Adewumi · Journal of Advances in Biology & Biotechnology · 2025

Bile duct cancer (cholangiocarcinoma) is a rare but aggressive malignancy with a poor prognosis and limited treatment options. Fibroblast growth factor receptor 1 (FGFR1), a key regulator of tumour growth and angiogenesis, has been identified as a plausible therapeutic target. Du...

Open access Research Article 10.9734/jabb/2025/v28i62497

In-silico Evaluation of Allium sativum Derived Phytochemicals Reveals Promising Drug Candidates for p53-MDM2 Interaction in Osteosarcoma Therapy

Atanda Opeyemi Emmanuel, Adesikun Aanu Adedamola, Adeyeye Pius Oluwaseyi, Oyewale Malik Tomilola & Adeyemi Mary Adewumi · Journal of Applied Life Sciences International · 2025

Osteosarcoma is a rare but aggressive bone cancer with poor prognosis, largely due to chemoresistance and the absence of effective targeted therapies. The MDM2 oncoprotein, a negative regulator of the p53 tumour suppressor, has emerged as a key driver of osteosarcoma progression...

Open access Research Article 10.9734/jalsi/2025/v28i4702