Omoighele F. Akhigbe

Environmental Genotoxins and Human Health Risks: Exposure Pathways, Mechanisms, Biomarkers and Challenges for Causal Risk Assessment

Omoighele F. Akhigbe, Ojogbane M. Abutu, Nyejirime Y. Wike, Elvis N. Shu & Irene Shuneba · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Environmental genotoxins are exogenous chemical agents or complex particulate mixtures capable of damaging DNA, chromosomes or genome-maintenance systems. Their public-health importance extends beyond cancer because persistent or poorly repaired lesions may contribute to reproduc...

Open access Research Article 10.9734/ajrimps/2026/v15i3406

Reducing Sugar, Alkaloid and Tannin from Dryopteris dilatata Fractions Modulates Diabetogenic and Oxidative Stress Activity on Alloxan Induced Diabetic Rats

Ajirioghene E. Akpotu, Samuel I. Ghasi, Amalachukwu O. Ike, Omoighele F. Akhigbe, Micheal A. Amadi, Daniel O. J. Ajah, Funso-Babarimisa, Funso, Victoria O. Chukwu & Martins U. Ukiwa · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2024

Active components in medicinal plants possess therapeutic indications in disease states. Aim: The present investigation evaluated the activity of fraction from Dryopteris dilatata leaves modulating diabetogenic and oxidative stress activity in alloxan-induced diabetic Rats. Metho...

Open access Research Article 10.9734/ajrimps/2024/v13i3259

Attenuating Effect of Fraction of Dryopteris dilatata on Alloxan-induced Oxidative Stress and Hepato-nephro Injury in Wistar Rat Models

Ajirioghene E. Akpotu, Samuel I. Ghasi, Ehoro O. Odu, Victoria O. Chukwu, Omoighele F. Akhigbe, Micheal A. Amadi, Oghenefejiro F. Ovowa & Destiny E. Omorhienrhien · European Journal of Medicinal Plants · 2025

Aims: Prolonged hyperglycemia leads to diabetes mellitus, causes serious complications which is a major concern affecting global economy.  Dryopteris dilatata (Dd) leaf contains phytochemicals with capacity to treat metabolic disorders.  The present study was carried out to evalu...

Open access Research Article 10.9734/ejmp/2025/v36i41285