Olusola Olalekan Elekofehinti

Hypoglycemic, Hypolipidemic and Antioxidant Potentials of Aqueous and Ethanolic Leaf Extracts of Anacardium occidentale in Alloxan Induced Type I Diabetic Rat Model

Olusola Olalekan Elekofehinti, Richard Oseh Osehodion, Tolulope Tosin Adeyelu, Tomisin Happy Ogunwa, Isaac Olatunde, Omosigho Aiwuyo & Oluwamodupe Cecilia Ejelonu · Journal of Advances in Medicine and Medical Research · 2016

Aim: The current study investigated the hypoglycemic, antioxidant and hypolipidemic effects of the aqueous and ethanolic leaf extracts of Anarcardium occidentale in alloxan-induced diabetic rats. Study Design: In vivo experiment. Place and Duration of Study: Department of Biochem...

Open access Research Article 10.9734/BJMMR/2016/24357

In silico Studies on Plant Derived Rutin as Potent Agonist of Peroxisome Proliferator-activated Receptor Gamma (PPARγ)

Olusola Olalekan Elekofehinti · Journal of Advances in Medicine and Medical Research · 2016

Aims: Peroxisome proliferator-activated receptor gamma (PPARγ) agonists are beneficial in the management of diabetes by increasing insulin sensitivity and inhibiting hepatic gluconeogenesis. The aim of the present study was to investigate PPAR-γ agonist property of rutin, a flavo...

Open access Research Article 10.9734/BJMMR/2016/23813

Functional Compounds of Lobelia inflata Revealed Novel Potential Targets for Chronic Cough Therapy

Toluwase Hezekiah Fatoki, Olusola Olalekan Elekofehinti, Afolabi Clement Akinmoladun & David Morakinyo Sanni · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Aim: To identify potential targets involved in chronic cough pathophysiology toward discovery and development of new therapeutants. Methodology: This work was carried out on bioactive compounds of selected medicinal plants with reference to known therapeutic agents using computat...

Open access Research Article 10.9734/JAMPS/2018/45276

In silico Study of Ornithine Decarboxylase and HSP-90 Gene in the Anti-trypanosomal Activities of Annona muricata Annonaceae

Innocent Bamidele Osho, Isaac Abayomi Adebayo, Olusola Olalekan Elekofehinti & Catherine Olusunmibola Durojaye · Journal of Advances in Medical and Pharmaceutical Sciences · 2023

Aims: Trypanosomiasis is one of the neglected tropical diseases of Sub-Saharan Africa caused by the numerous species and sub-species of the protozoan genus Trypanosoma. Soursop, also known as Annona muricata (Annonaceae), is a prevalent tropical plant species renowned for its num...

Open access Research Article 10.9734/jamps/2023/v25i4611