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Olubukola Sinbad Olorunnisola

Publications (6)

Acute and Sub-acute Toxicity Assessment of Euphorbia lateriflora (Schum and Thonn) in Wistar Albino Rats

Olubukola Sinbad Olorunnisola, Adewale Adetutu, Abiodun Olusoji Owoade, Folorunsho Ayodeji Ajayi, Adedoyin Adetutu Ajibade & Peter Adegbola · European Journal of Medicinal Plants · 2019

Aims: The toxicity of ethanol whole plant extract of Euphorbia lateriflora was assessed in Albino Wistar rats. Methodology: The LD50 was at single dose of 5000 mg/kg body weight, the sub-acute dosage of the extract was administered orally at 250 and 500 mg/kg b.w.t twice daily fo...

Open access Research Article 10.9734/ejmp/2019/v29i130147

Seasonal GC-MS Profiling and in silico Screening of Vernonia amygdalina Metabolites against Angiotensin-Converting Enzyme and Arginase

Adebola Olayemi Akintola, Olubukola Sinbad Olorunnisola, Uthman Abiola Laoye & Kehinde David Busuyi · Asian Journal of Research in Biochemistry · 2026

Hypertension remains a major global health burden, and plant-derived products continue to be investigated as sources of bioactive compounds. Vernonia amygdalina Delile has documented experimental cardiovascular and angiotensin-converting enzyme (ACE)-related activity, but the ext...

Open access Research Article 10.9734/ajrb/2026/v16i5526

Investigation of Hepatoprotective and Antioxidant Activity of Celosia argentea against Tissue Injury Caused by Rifampicin Administration

Abiodun Olusoji Owoade, Adewale Adetutu, Olubukola Sinbad Olorunnisola & Olufemi Ogundeji Ogundipe · Journal of Applied Life Sciences International · 2019

This study evaluated the antioxidant and possible protective effects of Celosia argentea against tissue injury caused by rifampicin administration. The antioxidant property of the aqueous extract of C. argentea was assessed in-vitro using 2,2-Diphenyl-1- picrylhydrazyl (DPPH), an...

Open access Research Article 10.9734/jalsi/2018/v19i430068

Hypoglycemic and Anti-hyperlipidaemia Effects of Methanolic Extract of Zingiber officinale and its Role in Ameliorating Oxidative Stress in Alloxan-induced Diabetic Rats

Abiodun Olusoji Owoade, Adewale Adetutu & Olubukola Sinbad Olorunnisola · Journal of Pharmaceutical Research International · 2017

This study was designed to examine the hypoglycemic and antioxidant defense by methanolic extract of Zingiber officinale on alloxan induced diabetes in Wistar rats.The preliminary study showed that Z. officinale extract was able to scavenge the 2,2-Diphenyl-1-picrylhydrazyl (DPPH...

Open access Research Article 10.9734/JPRI/2017/34396

Antioxidant Potential of Polyphenol Rich Extract from Hibiscus sabdariffa

Abiodun Olusoji Owoade, Adewale Adetutu & Olubukola Sinbad Olorunnisola · Journal of Advances in Medicine and Medical Research · 2016

Aims: Hibiscus sabdariffa is a medicinal plant species that is consumed for its health benefits in Africa, therefore this study investigated the antioxidant properties of Hibiscus polyphenolic rich extract (HPE), prepared from Hibiscus sabdariffa. Place and Duration of Study: Sch...

Open access Research Article 10.9734/BJMMR/2016/26742

Codeine-mediated Haematoxicity, Hepatotoxicity and Nephrotoxicity in Male Albino Rats

Abiodun Olusoji Owoade, Abdulrahman Abdullateef, Adewale Adetutu & Olubukola Sinbad Olorunnisola · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2019

Objectives: This study aimed to investigate the effects of codeine administration on some haematological and biochemical indices in rats. Materials and Methods: Therapeutic dose (5 mg/kg/day), high dose (25 mg/kg/day) and extreme dose (50 mg/kg/day) of codeine were administered o...

Open access Research Article 10.9734/ajrimps/2019/v6i330102