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Okwudili B. Nwankwo

Publications (4)

Malaria in Pregnancy Induces a Pro-inflammatory Cytokine Milieu: Comparative Analysis with Non-infected Pregnant and Non-pregnant Women

Emmanuel Ifeanyi Obeagu & Okwudili B. Nwankwo · Asian Journal of Immunology · 2026

Background: Malaria in pregnancy is associated with adverse maternal and fetal outcomes, partly driven by immune dysregulation and altered cytokine responses. Pro-inflammatory and anti-inflammatory cytokines influence disease severity, yet their precise profiles in malaria-infect...

Open access Research Article 10.9734/aji/2026/v9i1186

Red Cell Functional Plasticity in Gestation: Beyond Indices to Oxygen-Sensing and Rheology

Emmanuel I. Obeagu & Okwudili B. Nwankwo · International Journal of Research and Reports in Hematology · 2026

Background: Pregnancy induces coordinated hematologic adaptations to sustain maternal–fetal oxygen exchange. While clinical assessment traditionally relies on red cell indices such as hemoglobin concentration, hematocrit, and mean corpuscular volume, these static measures incompl...

Open access Research Article 10.9734/ijr2h/2026/v9i1216

Beyond Hemoglobin S: Systems Biology Insights into the Multisystem Nature of Sickle Cell Disease: A Narrative Review

Emmanuel I. Obeagu & Okwudili B. Nwankwo · International Journal of Research and Reports in Hematology · 2026

Background: Sickle cell disease (SCD) is classically defined by a single-point mutation in the β-globin gene leading to hemoglobin S polymerization and erythrocyte sickling. However, accumulating evidence indicates that SCD is a complex multisystem disorder characterized by chron...

Open access Research Article 10.9734/ijr2h/2026/v9i1212

Hematological Profiles and Prognostic Markers in Pediatric Hematologic Malignancies: A Narrative Review

Emmanuel Ifeanyi Obeagu & Okwudili B. Nwankwo · Asian Hematology Research Journal · 2026

Pediatric hematologic malignancies, including acute leukemias and lymphomas, represent the most common cancers in childhood and are associated with variable clinical outcomes despite major therapeutic advances. Hematological profiles derived from peripheral blood and bone marrow...

Open access Research Article 10.9734/ahrj/2026/v9i1236