Okolie Lucy Janefrancis

The Role of Trained Immunity in Protection against Infectious Diseases: Epigenetic Reprogramming and Long-term Immune Responses

Okolie Lucy Janefrancis, Maduka Amuche Stella, Ojeniran Taiwo Paul, Yahaya Imran Umar, Lawal Mustapha, Oniye Mariam Masud & Umar Muhammad Muhsin · Asian Journal of Immunology · 2025

Trained immunity, a concept introduced more than a decade ago, defines the non-specific memory capacity of innate immunity by epigenetic and metabolic reprogramming. It involves features of epigenetic and metabolic reprogramming of innate immune cells that induce long-term functi...