CRISPR Gene Editing Strategies for Targeting Oncogene Addiction in Colorectal Cancer
Fortune Itoje Ebiala, Jumoke Ologun, John Kelenna Iregbu, Ogochi Blessing Chukwuneke, Aliaa Mohammed Mahmoud Soliman, Ayo Ebunolorun Ibukunoluwa, Rasheedat A. Busari MD, Oluwatobiloba Kehinde Adedokun & Lawrence John AJutor · Journal of Cancer and Tumor International · 2025
Background: Oncogene addiction occurs in most tumour cells it is a phenomenon capable of driving colorectal cancer (CRC) growth, where tumour cells rely on genes like KRAS, BRAF, or MYC to survive. This has been so far seen as an exploitable target for precision therapies. Aim: T...
Open access
Research Article
10.9734/jcti/2025/v15i3316