Obi Ifeanyi Malachy

Annona muricata Ethanolic Leaf Extract Attenuates Dexamethasone Induced Oxidative Stress, Dyslipidemia and Hepatotoxicity in Rats through Upregulation of Endogenous Antioxidant Enzymes and Lipid Profile Normalization

Obi Ifeanyi Malachy, Chilaka Kingsley Chimsorom, Obi Helen Chinonyelum, Chilaka Jane Ugochinyere, Obi Frances Somtochukwu & Imolede Ohiomoje Isaac · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: The therapeutic use of dexamethasone is often associated with adverse effects such as oxidative stress, dyslipidemia, and hepatotoxicity, primarily due to the generation of reactive oxygen species and disruption of metabolic homeostasis. Natural plant‑based antioxidan...