O. M. Ighodaro

Phytochemical Distribution and Antimicrobial Sensitivity of Sapium ellipticum (Hochst.) Pax Leaf Extracts

O. M. Ighodaro, O. A. Akinloye, J. A. Popoola & S. A. Adebodun · European Journal of Medicinal Plants · 2018

In this study, different extract fractions (aqueous, ethanol, methanol, hexane, diethyl ether and chloroform) of Sapium ellipticum (SE) leaf obtained by cold extraction method were screened for phytochemicals, and antimicrobial sensitivity. The percentage yield of extract was hig...

Open access Research Article 10.9734/EJMP/2018/8252

Antioxidant Potentials of L-Ascorbic Acid (L-AA) and Butylated Hydroxytoluene (BHT) in CCl4-Induced Oxidative Damage of Soft Tissues in Wistar Rats

O. M. Ighodaro, J. O. Omole, A. O. Aminu, A. M. Adeosun & A. I. Ogunlana · Chemical Science International Journal · 2016

The antioxidant potentials of Butylated hydroxytoluene (BHT) and L-Ascorbic acid (L-AA) in CCl4-induced tissue damage were compared in adult female Wistar rats. Toxicity was induced in the animals via a single dose (i.p) of 20% 2 mL/Kg body weight (BW) of CCl4. BHT and L-ascorbic...

Open access Research Article 10.9734/ACSJ/2016/16762

Sapium ellipticum (Hochst.) Pax Leaf Extract: In-vitro Antioxidant Activities and Lethal Dose (LD50) Determination in Wistar Rats

O. M. Ighodaro & O. A. Akinloye · Journal of Advances in Medicine and Medical Research · 2016

Prior to this investigation, the LD50 and antioxidant activities of Sapium ellipticum leaf extract have not been reported, hence; the focus of this study. The LD50 of the extract was determined through three routes of administration using the method of Lorke. The Intraperitoneal...

Open access Research Article 10.9734/BJMMR/2016/8253