Nsikak M. Umoh

Neuroprotective Effect of Dacryodes edulis Ethanolic Leaf Extract on the Hippocampus of Rats of Ketamine-Induced Neurotoxicity

Sadeyeng E. Anani, Williams A. Nnenna, Eric A. Agaba, Nsikak M. Umoh, Ifiok F. Bassey, Eru M. Eru, Michael E. Oku, Kelechi C. Uruakpa, Paul A. Odey, Theresa E. Isamoh, Cletus U. Ajang, Gideon Uzor, Gabriel U. Udo-affah & Anozeng O. Igiri · Asian Journal of Research and Reports in Neurology · 2024

Introduction: The brain is an organ that is responsible for knowledge acquisition, cognition and control of body movements. Its normal functioning and structure can be affected by exposure to drugs of abuse (for example ketamine) which can cause disorder in the nervous system. Me...

Open access Research Article

Ameliorative Effect of Curcuma longa Ethanolic Extract on the Histology, Hepatic Glycogen Content and Some Biochemical Parameters of the Liver in Streptozotocin-Induced Hyperglycemic Wistar Rats

Mfon I. Akpaso, Lydia E. Bassey, Sadeyeng E. Anani, Michael E. Oku, Williams A. Nnenna, Nsikak M. Umoh, Eru M. Eru, Elton N. Takim, Gideon Uzor, Theresa E. Isamoh & Eric A. Agaba · Journal of Complementary and Alternative Medical Research · 2024

Introduction: Diabetes mellitus is a life threatening disease that requires immediate medical treatment. Numerous medicinal plants have been known for their anti-diabetic effects and Curcuma longa (turmeric) is one of them. This attribute is possible due to the pharmacological pr...

Open access Research Article 10.9734/jocamr/2024/v25i11579

Effect of Alkaloid-rich Fraction of Dacryodes edulis Leaves on the Cytoachitecture of the Liver and Blood Glucose Levels in Streptozotocin-Induced Hyperglycemic Rats

Mfon I. Akpaso, Sadeyeng E. Anani, Theresa E. Isamoh, Eric A. Agaba, Michael E. Oku, Kelechi Uruakpa, Nsikak M. Umoh, Katherine K. Eteng, Eru E. Mba & Cletus U. Ajang · Asian Journal of Research and Reports in Hepatology · 2025

Introduction: Diabetes mellitus is a chronic disease characterized by hyperglycemia due to insufficient insulin production or action. Numerous medicinal plants have been known for their anti-diabetic effects and Dacryodes edulis is one of them. Its extracts have been known for th...

Open access Research Article 10.9734/ajrrhe/2025/v7i149

Lipid Peroxidation and Glutathione Level Following Scopolamine-Induced Cognitive Dysfunction in Rats: Potentials of Telfairia occidentalis Seeds and Talinium triangulare Leaves Aqueous Extracts

Samson O. Paulinus, Eru M. Eru, Gabriel U. Udo-affah, Michael E. Oku, Ifiok Bassey, Kelechi C. Uruakpa, Nsikak M. Umoh, Michael Ajen, Sadeyeng E. Anani & Anozeng O. Igiri · Asian Journal of Research and Reports in Neurology · 2024

Background: Oxidative stress augmented with progressive age, causes changes in mitochondrial DNA, mitochondrial disruption and more oxidative trouble. This process is facilitated in Alzheimer’s disease by the pathology of αβ amyloid and activated microglia. Objectives: The presen...

Open access Research Article

Effect of Alkaloid-rich Fraction of Dacryodes edulis Leaves on the Microstructure of the Hippocampus and Blood Glucose Levels of STZ-Induced Diabetic Wistar Rats

Eru, E.M, Theresa I. Ekpenyong, Cyril A. Agbor, Christie E. Fischer, Michael E. Oku, Samson O. Paulinus, Etim D. Isaiah, Kelechi C. Uruakpa, Williams A. Nnenna, Nsikak M. Umoh, Eric A. Agaba & Anozeng O. Igiri · International Neuropsychiatric Disease Journal · 2025

Aim: the aim of this study was to elucidate the effect of alkaloid-rich fraction of Dacryodes edulis on body weight, blood glucose level and the microanatomy of the hippocampus of STZ-induced Diabetic Wistar rats. Methodology: 25 adult male Wistar rats were used for the experimen...

Open access Research Article 10.9734/indj/2025/v22i3477