Activation of Nrf2 Restores Klotho Expression and Attenuates Oxidative Stress and Inflammation in CKD
Young Ki Son, Shu-Man Liu, Seyed H Farzaneh, Sohrab Nazertehrani, Mahyar Khazaeli & Nosratola D. Vaziri · Journal of Applied Life Sciences International · 2014
Background: Chronic kidney disease (CKD) causes klotho deficiency, oxidative stress and inflammation which are common features and major mediators of progression of renal disease. Oxidative stress in CKD is, partly, due to impaired activation of Nrf2, the master regulator of gene...
Open access
Research Article
10.9734/JALSI/2015/13745