Ngozi Patricia Ebosie

Insilico Docking Analysis of Antimalarial and Anticancer Potentials of a Hydrazone Derivative of 2-Amino-4-Thiazoleacetic Acid Hydrazide

Ngozi Patricia Ebosie, Beniah Obinna Isiuku & Pauline Amaka Nnagbo · South Asian Research Journal of Natural Products · 2025

2-amino-4-thiazoleacetic acid hydrazide (ATAH) was prepared from the reaction of ethyl-2-amino-4-thiazoleacetate with hydrazine hydrate. The hydrazone derivative, 2-(2-amino-1,3-thiazol-4-yl)-N'-[(E)-(4-methoxyphenyl)methylidene]acetohydrazide (ATAPH) was synthesized by the conde...