The Antiangiogenic Effects of Tamoxifen might be Attributed to Receptor Binding Capacity of its Solvent Dimethylsulfoxide in Breast Cancer: A Molecular Docking Study
Orhan Koçak, Nazlı Deniz Taşkın & Ece Şimşek · Journal of Pharmaceutical Research International · 2019
Aim: Tamoxifen, a Dimethyl sulfoxide (DMSO)-soluble chemotherapeutic, is widely used in the treatment of breast cancer. Tamoxifen has an anti-angiogenic effect especially on breast tumor cells by blocking VEGF(Vascular Endothelial Growth Factor) production. On the other hand, acc...
Open access
Research Article
10.9734/jpri/2019/v30i230265