Synthesis, Molecular Modelling and Biological Evaluation of Novel Pyrimidine Derivatives as Anti-inflammatory Agents
Naglaa Mohamed Ahmed, Shahira Nofal & Samir Mohamed Awad · Journal of Pharmaceutical Research International · 2020
Aim: As part of ongoing studies in developing new anti-inflammatory agents, 2-thioxo-1,2,3,4-tetrahydropyrimidine derivative 1 was synthesized by direct Biginelli condensation and used for the synthesis of novel series of pyrimidin-2-thione derivatives (2a-d to 7a-b). Materials...
Open access
Research Article
10.9734/jpri/2020/v32i2230771