Nagla A. El-Shitany

Activation of Sirtuin 1 by Ellagic Acid Ameliorates Cisplatin-Induced Apoptosis, Oxidative Stress and Nephrotoxicity

Thikryat Neamatallah, Basma G. Eid, Amina M. Bagher, Mohammed Z. Nasrullah, Soad S. Ali, Zuhair M. Mohammedsaleh & Nagla A. El-Shitany · Journal of Pharmaceutical Research International · 2021

Background: Cisplatin (Cis) is a chemotherapeutic agent commonly applied in treating different cancers. However, acute renal injury remains a major side effect of Cis that limits its clinical use. Oxidative stress in renal tissues play a key role in Cis-induced toxicity. This res...

Open access Research Article 10.9734/jpri/2021/v33i1531283

Optimizing the Use of Hydroxychloroquine in the Management of COVID-19 Given Its Pharmacological Profile

Ahmed S. Ali, Mahran S. Abdel-Rahman, Riyadh S. Almalikil, Abir S. Mohamed, Khalid A. Alfaifi, Abdelbabgi El. Fadil, Nagla A. El-Shitany & Huda M. Alkreathy · Journal of Pharmaceutical Research International · 2020

After the global pandemic of the new coronavirus, its rapid spread and many victims, it is necessary to find an effective vaccine or drugs to overcome it. Most specialists consider that repositioning some medications is the best, fastest and most reliable option for treating pati...

Open access Research Article 10.9734/jpri/2020/v32i830468