The Effect of Silymarin on Serum Concentration of Soluble Apoptosis Markers in β-Thalassemia Major Patients Receiving Desferrioxamine
Nafiseh Esmaeil, Marjan Gharagozloo, Behjat Moayedi, Milad Mirmoghtadaei & Mahdi Ghatreh Samani · Journal of Advances in Medical and Pharmaceutical Sciences · 2014
Background: Despite appropriate chelation therapy with desferrioxamine, iron deposition in visceral organs causes tissue damage in thalassemia major patients. Excess iron can generate reactive oxygen species (ROS) that may lead to cell death and apoptosis. Therefore, antioxidants...
Open access
Research Article
10.9734/JAMPS/2015/12818